Norwegian research project aims to find cure for endometriosis with innovative techniques in Trondheim

A Norwegian research project led by Sintef is embarking on a mission to find a cure for endometriosis, a condition that affects approximately one in ten women in Norway. Current treatments primarily focus on pain relief without addressing the underlying issue. Researchers aim to apply cancer research techniques to study endometriosis, as it shares characteristics with cancer in that abnormal cells proliferate in inappropriate locations within the body.

The project, set to begin in January and running for four years with a budget of 15 million kroner, includes collaboration with institutions such as St. Olavs hospital and Oslo University Hospital. The initiative seeks to deepen the understanding of a condition that brings significant suffering to many Norwegian women.

In the lab at Gløshaugen in Trondheim, samples from hundreds of women will be analyzed. Current treatment options are limited, with some women benefiting from hormonal birth control while others may undergo surgical removal of abnormal tissue.

One innovative aspect of the research involves making endometriosis tissue “fluoresce,” which would help surgeons distinguish between healthy and diseased tissue during operations. This approach could simplify the surgical procedure significantly.

The study will also allow the testing of various medications on patient-derived cells, which could guide future drug development. Researchers are particularly interested in examining the effects of existing medications, including those used for migraines, on endometriosis.

The complexities of developing effective treatments for endometriosis arise from the variability in patient experiences. The research aims to pave the way for individualized treatment options and improve overall care for those affected by this challenging condition.